Typical timeline and physiological and psychological changes of post-ejaculatory depression (PCD) Historical literature records Global prevalence Symptom grading (PCD Severity Index, PSI) Psychological factors Sociocultural factors Pathological and physiological factors Six core mechanisms Brain imaging evidence (2024 Nature Neuroscience) Risk factor scale (total score 0-36, score ≥18 requires assessment) Differential diagnosis Treatment pyramid (5 levels) Prevention and self-management 30...